CBDPetsCBD in the veterinary field

Using CBD In The Veterinary Field

While the health benefits CBD provides to people are wide-known, there is also a lot of research highlighting how this cannabis compound can help animals. Holistic veterinarians have been reporting that pets can experience therapeutic benefits from CBD pet tinctures and CBD pet treats for years. With legalization, researchers are now performing even more research, showing the benefits of using CBD in the veterinary field and analyzing the science behind its use.

 

As legalization becomes more widespread, pet owners are becoming more curious about how CBD-infused pet products can be used to treat their pets’ ailments. Throughout this article, we’ll shed some light on the benefits CBD can provide when used in the veterinary field and the research backing its successes in treating animals.

1. CBD Shows Promise In Treating Animal Seizures And Epilepsy

With so many dogs suffering from seizures, it’s possible to treat dogs using CBD because of its ability to control seizures and epilepsy. The majority of dogs who have seizures are given drugs that assist in managing the seizures, but not without a cost. With the main drugs issued to dogs to control seizures, phenobarbital and potassium bromide, the dogs’ livers are being damaged. These drugs are not always effective, meaning damage might be done without any improvements.

 

Some studies show treatment-resistant epilepsy can be treated with CBD. Animal studiesshow that CBD is effective as an anticonvulsant in multiple species and models. When similar studies were conducted in children with treatment-resistant epilepsy, the conclusion was that CBD is a promising treatment. Another studyshowed CBD improving seven out of eight epileptics’ disease state.

2. CBD Combats Neurodegenerative Diseases CBD also helps patients with various neurodegenerative diseases by providing neuroprotection in cortical neuron cultures. With the introduction of this powerful antioxidant, it’s possible to provide brain cells with the protection they need to avoid damage from neurodegenerative diseases. In essence, dogs suffering from degenerative myelopathy and various other kinds of spine and nerve problems can experience therapeutic relief from the symptoms as well. One studyexamined how rat cortical neuron cultures reacted when treated with CBD after being exposed to toxic levels of glutamate, an excitatory neurotransmitter. When the rats were given CBD, there was an observable decrease in the level of glutamate toxicity. The CBD was found to be an antioxidant by cyclic voltammetry. It prevents hydroperoxide-induced oxidate damage in the same way or better than other antioxidants found in neuronal cultures and Fenton reaction systems. With this study, the data suggests CBD is a potent antioxidant that could be useful for treating oxidative neurological disorders. 3. CBD Can Help Animals With Inflammatory Bowel Disease There is evidencesuggesting that cannabinoids are capable of alleviating intestinal inflammation and cancer too. Patients with inflammatory bowel disease and colon cancer have been analyzed, showing adaptive changes in the endocannabinoid system. The cannabinoids exert antiproliferative, apoptotic, and antimetastatic effects. They also lessen cytokine releases and promote wound healing. CBD, in particular, has been used to aid mice with their inflammatory hypermotility. In one study, croton oil was used to induce intestinal inflammation in mice. Researchers found that CBD introduction resulted in a reduction in intestinal motility in the croton oil-treated mice. 4. CBD Combats Chronic Inflammation And Reduces The Chance Of Developing Autoimmune Disease The use of CBD is connected to inflammatory cytokines, resulting in a decrease in their production and release. These cytokines contribute to the development of several issues, including hypersensitivities, autoimmunity, and allergies. In a study,conducted to analyze CBD’s anti-inflammatory effects, this compound was the most effective cannabinoid for reducing inflammation when given as a dose of 100 micrograms/kg. Th17 phenotype increases in autoimmune inflammatory pathologies. With this being said, CBD introductionsuppresses the production and secretion of this detrimental cytokine. Other significant components in the induction of Th17, mRNA and protein of IL-6, saw decreases as well. An anti-inflammatory called cytokine IL-10 increases in production as a result of subjects being pretreated with CBD too. Thus, CBD has been proven to suppress primary contributors to autoimmune disease while promoting anti-inflammatory production. 5. CBD Improves Cardiovascular Health One studyshows that CBD helps with cardiovascular health too. Rats given CBD before inducing ischemia experienced a reduction in the number of ischemia-induced arrhythmias and a reduction in infarct size. When CBD was introduced to the rats before the researchers induced reperfusion, the rats’ infarct size was reduced as well. In essence, CBD is a cardioprotective compound because it lessens ventricular arrhythmias and attenuates infarct size. Another studyexamines the hemodynamic impacts of CBD on rats conditioned with and without fear. CBD introduction resulted in a decrease in the mean arterial blood pressure without impacting the conditioned rats’ heart rates. The researchers found that with the introduction of CBD, there was a noticeable reduction in the cardiovascular response the fear-conditioned rats had to anxiety and stressful situations. 6. CBD Improves Appetite And Decreases Nausea According to the National Cancer Institute, “It is believed that the endogenous cannabinoid system may serve as a regulator of feeding behavior.” With this in mind, CBD acts as an appetite stimulator. CB1 receptors in the hypothalamus could also be involved in motivating or rewarding eating. This is backed by evidenceshowing CB1 receptors even play a primary role in oral motor control for suckling throughout neonatal development. In turn, this shows the importance of the stimulation of these receptors. Since CBD stimulates these receptors, appetite stimulation is the result. Through a study analyzing the anti-nausea effects of CBD on rats, the results highlight CBD’s ability to suppress vomiting too. With the completion of this study, the researchers found that CBD diminishes nausea induced by nicotine, lithium chloride, and cisplatin. Concluding On Using CBD In The Veterinary Field Although CBD can provide therapeutic relief to animals, some animals’ cannabinoid systems contain more cannabinoid receptors than others. This means CBD can be more potent to some animals, resulting in toxicity if caution is not taken. While treating your pets with CBD is an option, no one should provide treatment to an animal without first consulting a veterinarian. CBD is rapidly becoming the go-to therapeutic treatment for humans and their pets. With more research regarding how CBD reacts with the endocannabinoid system, more therapeutic impacts are being uncovered and observed.

2. CBD Combats Neurodegenerative Diseases

CBD also helps patients with various neurodegenerative diseases by providing neuroprotection in cortical neuron cultures. With the introduction of this powerful antioxidant, it’s possible to provide brain cells with the protection they need to avoid damage from neurodegenerative diseases. In essence, dogs suffering from degenerative myelopathy and various other kinds of spine and nerve problems can experience therapeutic relief from the symptoms as well.

 

One studyexamined how rat cortical neuron cultures reacted when treated with CBD after being exposed to toxic levels of glutamate, an excitatory neurotransmitter. When the rats were given CBD, there was an observable decrease in the level of glutamate toxicity.

 

The CBD was found to be an antioxidant by cyclic voltammetry. It prevents hydroperoxide-induced oxidate damage in the same way or better than other antioxidants found in neuronal cultures and Fenton reaction systems. With this study, the data suggests CBD is a potent antioxidant that could be useful for treating oxidative neurological disorders.

3. CBD Can Help Animals With Inflammatory Bowel Disease

There is evidencesuggesting that cannabinoids are capable of alleviating intestinal inflammation and cancer too. Patients with inflammatory bowel disease and colon cancer have been analyzed, showing adaptive changes in the endocannabinoid system. The cannabinoids exert antiproliferative, apoptotic, and antimetastatic effects. They also lessen cytokine releases and promote wound healing.

 

CBD, in particular, has been used to aid mice with their inflammatory hypermotility. In one study, croton oil was used to induce intestinal inflammation in mice. Researchers found that CBD introduction resulted in a reduction in intestinal motility in the croton oil-treated mice.

CBD Combats Chronic Inflammation And Reduces The Chance Of Developing Autoimmune Disease

4. CBD Combats Chronic Inflammation And Reduces The Chance Of Developing Autoimmune Disease

The use of CBD is connected to inflammatory cytokines, resulting in a decrease in their production and release. These cytokines contribute to the development of several issues, including hypersensitivities, autoimmunity, and allergies. In a study,conducted to analyze CBD’s anti-inflammatory effects, this compound was the most effective cannabinoid for reducing inflammation when given as a dose of 100 micrograms/kg.

 

Th17 phenotype increases in autoimmune inflammatory pathologies. With this being said, CBD introductionsuppresses the production and secretion of this detrimental cytokine. Other significant components in the induction of Th17, mRNA and protein of IL-6, saw decreases as well. An anti-inflammatory called cytokine IL-10 increases in production as a result of subjects being pretreated with CBD too. Thus, CBD has been proven to suppress primary contributors to autoimmune disease while promoting anti-inflammatory production.

5. CBD Improves Cardiovascular Health

One studyshows that CBD helps with cardiovascular health too. Rats given CBD before inducing ischemia experienced a reduction in the number of ischemia-induced arrhythmias and a reduction in infarct size. When CBD was introduced to the rats before the researchers induced reperfusion, the rats’ infarct size was reduced as well. In essence, CBD is a cardioprotective compound because it lessens ventricular arrhythmias and attenuates infarct size.

 

Another studyexamines the hemodynamic impacts of CBD on rats conditioned with and without fear. CBD introduction resulted in a decrease in the mean arterial blood pressure without impacting the conditioned rats’ heart rates. The researchers found that with the introduction of CBD, there was a noticeable reduction in the cardiovascular response the fear-conditioned rats had to anxiety and stressful situations.

6. CBD Improves Appetite And Decreases Nausea

According to the National Cancer Institute, “It is believed that the endogenous cannabinoid system may serve as a regulator of feeding behavior.” With this in mind, CBD acts as an appetite stimulator.

 

CB1 receptors in the hypothalamus could also be involved in motivating or rewarding eating. This is backed by evidenceshowing CB1 receptors even play a primary role in oral motor control for suckling throughout neonatal development. In turn, this shows the importance of the stimulation of these receptors. Since CBD stimulates these receptors, appetite stimulation is the result.

 

Through a study analyzing the anti-nausea effects of CBD on rats, the results highlight CBD’s ability to suppress vomiting too. With the completion of this study, the researchers found that CBD diminishes nausea induced by nicotine, lithium chloride, and cisplatin.

Concluding On Using CBD In The Veterinary Field

Although CBD can provide therapeutic relief to animals, some animals’ cannabinoid systems contain more cannabinoid receptors than others. This means CBD can be more potent to some animals, resulting in toxicity if caution is not taken. While treating your pets with CBD is an option, no one should provide treatment to an animal without first consulting a veterinarian.

 

CBD is rapidly becoming the go-to therapeutic treatment for humans and their pets. With more research regarding how CBD reacts with the endocannabinoid system, more therapeutic impacts are being uncovered and observed.

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